Ruijin Shao

Projects | Publications

Position: Assistant Professor

Title: M.D. Ph.D.

E-mail: ruijin.shao@fysiologi.gu.se

Project: Molecular and Cellular Aspects of the Human and Rodent Fallopian Tubes: the Central Roles of Estrogen/Estrogen Receptor Signalling Pathway in the Regulation of Tubal Function in Health and Disease

Address
Institute of Neuroscience and Physiology
Dept. of Physiology/Endocrinology
The Sahlgrenska Academy at University of Gothenburg
Medicinaregatan 11
P.O. Box 434, SE-405 30 Göteborg
SWEDEN
Phone +46 31 786 3408
Fax +46 31 786 3512

Publications

* Correspondence

1. Spatiotemporal expression of androgen receptors in the female rat brain during the oestrous cycle and the impact of exogenous androgen administration: a comparison with gonadally intact males *
   Feng Y, Weijdegård B, Wang T, Egecioglu E, Fernandez-Rodriguez J, Huhtaniemi I, Stener-Victorin E, Billig H and Shao R
   Molecular and Cellular Endocrinology 2010 accepted
    
2. Stromal cell-specific apoptotic and anti-estrogenic mechanisms may explain uterine defects in humans following clomiphene citrate therapy *
   Nutu M, Feng Y, Egecioglu E, Weijdegård B, Stener-Victorin E and Shao R
   The American Journal of Obstetrics & Gynecology 2010 accepted
    
3. Understanding the mechanisms of human tubal ectopic pregnancies: new evidence from knockout mouse models *
   Shao R
   Human Reproduction 2010 25:584-7
    
4. Hypothalamic neuroendocrine functions in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture
   Feng Y, Johansson J, Shao R, Mannerås L, Fernandez-Rodriguez J, Billig H, Stener-Victorin E.
   PLoS One 2009 4:e6638.
    
5. Down-regulation of cilia-localized IL-6Rα by 17β-estradiol in mouse and human fallopian tubes *
   Shao R, Nutu M, Karlsson-Lindahl L, Benrick A, Weijdegård B, Lager S, Egecioglu E, Fernandez-Rodriguez J, Gemzell-Danielsson K, Ohlsson C, Jansson J-O and Billig H
   The American Journal of Physiology - Cell Physiolology 2009 297:C140-51
    
6. Clomiphene citrate causes aberrant tubal apoptosis and estrogen receptor activation in rat fallopian tube: implications for tubal ectopic pregnancy *
   Shao R, Nutu M, Weijdegård B, Egecioglu E, Fernandez-Rodriguez J, Karlsson-Lindahl L, Gemzell-Danielsson K, Bergh C, and Billig H
   Biology of Reproduction 2009 80:1262-71
    
7. Liver-derived IGF-I enhances the androgenic response in prostate
   Svensson J, Kindblom J, Shao R, Movérare-Skrtic S, Lagerquist M, Andersson N, Sjögren K, Venken K, Vanderschueren D, Jansson JO, Isaksson O, and Ohlsson C
   Journal of Endocrinology 2008 199:489-97
    
8. Differences in prolactin receptor (PRLR) in mouse and human fallopian tubes: evidence for multiple regulatory mechanisms controlling PRLR isoform expression in mice *
   Shao R, Nutu M, Weijdegård B, Egecioglu E, Fernandez-Rodriguez J, Tallet E, Goffin V, Ling C, and Billig H
   Biology of Reproduction 2008 79:748-757
    
9. Dynamic regulation of estrogen receptor α isoform expression in the mouse fallopian tube: mechanistic insight into estrogen-dependent production and secretion of insulin-like growth factors *
   Shao R, Egecioglu E, Weijdegård B, Kopchick JJ, Fernandez-Rodriguez J, Andersson N, and Billig H
   The American Journal of Physiology - Endocrinology and Metabolism 2007 293:E1430-42
    
10. Ciliated epithelial-specific and regional-specific expression and regulation of the estrogen receptor β2 in the fallopian tubes of immature rats: a possible mechanism for estrogen-mediated transport process in vivo *
    Shao R, Weijdegård B, Fernandez-Rodriguez J, Egecioglu E, Zhu C, Andersson N, Thurin-Kjellberg A, Bergh C and Billig H
    The American Journal of Physiology - Endocrinology and Metabolism 2007 293:E147-E158
     
11. Estrogen-induced up-regulation of androgen receptor (AR) expression and enhancement of AR nuclear translocation in mouse fallopian tubes in vivo *
    Shao R, Ljungström K, Weijdegård B, Egecioglu E, Fernandez-Rodriguez J, Zhang FP, Thurin-Kjellberg A, Bergh C and Billig H
    The American Journal of Physiology - Endocrinology and Metabolism 2007 292:E604-E614
     
12. Developmental and hormonal regulation of progesterone receptor A-form expression in mouse lung in vivo: interaction with glucocorticoid receptors *
    Shao R, Egecioglu E, Weijdegård B, Ljungström K, Ling C, Fernandez-Rodriguez J and Billig H
    Journal of Endocrinology 2006 190: 857-870
     
13. Nuclear progesterone receptor (PR) A and B isoforms in mouse fallopian tube and uterus: implications for expression, regulation and cellular Function *
    Shao R, Weijdegård B, Ljungström K, Friberg A, Zhu C, Wang X, Zhu Y, Fernandez-Rodriguez J, Egecioglu E, Rung E and Billig H
    The American Journal of Physiology - Endocrinology and Metabolism 2006 291:E59-E72
     
14. Induction of apoptosis increases SUMO-1 protein expression and conjugation in mouse periovulatory granulosa cells in vitro *
    Shao R, Rung E, Weijdegård B and Billig H
    Molecular Reproduction and Development 2006 73:50-60
     
15. Progesterone receptor antagonists and statins decrease de novo cholesterol synthesis and increase apoptosis in rat and human periovulatory granulosa cells in vitro
    Rung E, Friberg PA, Shao R, Larsson DGJ, Nielson Ch. E, Svensson PA, Carlsson B, Carlsson MSL and Billig H
    Biology of Reproduction 2005 72:538-45
     
16. Increase of SUMO-1 expression in response to hypoxia: direct interaction with HIF-1α in adult mouse brain and heart in vivo
    Shao R, Zhang FP, Tian F, Friberg PA, Wang X, Sjöland H and Billig H
    FEBS Letters 2004 569:293-300
     
17. Inhibition of small ubiquitin-related modifier-1 by LH receptor stimulation is linked to induction of progesterone receptor during ovulation in mouse granulosa cells
    Shao R, Zhang FP, Rung E, Palvimo JJ, Huhtaniemi I and Billig H
    Endocrinology 2004 145:384-92
     
18. Gene expression analysis of prostate hyperplasia in mice overexpressing the prolactin gene specifically in the prostate
    Dillner K, Kindblom J, Flores-Morales A, Shao R, Törnell J, Norstedt G and Wennbo H
    Endocrinology 2003 144:4955-66
     
19. Suppression of apoptosis occurs in the cochlea by sound conditioning
    Niu X, Shao R and Canlon B
    NeuroReport 2003 14(7):1025-29
     
20. Expression of progesterone receptor (PR) A and B isoforms in mouse granulosa cells: stage-dependent PR-mediated regulation of apoptosis and cell proliferation
    Shao R, Markström E, Friberg PA, Johansson M and Billig H
    Biology of Reproduction 2003 68:914-21
     
21. Follicular development and apoptosis (Review)
    Billig H, Markström E, Svensson Ch. E, Shao R and Friberg PA
    In: Eppig J, Hegele-Hartung C, Lessl M (eds.), The future of the oocyte: basic and clinical aspects, vol. 41. Berlin: Springer; 2002: 23-41.
    Ernst Schering Research Foundation Workshop
     
22. Survival factors regulating ovarian apoptosis -- dependence on follicle differentiation (Review)
    Markström E, Svensson Ch. E, Shao R, Svanberg B and Billig H
    Reproduction 2002 123:23-30
     
23. Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells
    Svensson Ch. E, Markström E, Shao R, Andersson M and Billig H
    Fertility and Sterility 2001 76:1225-31