CV - Caroline Wass

Caroline Wass, PhD

Education / Degrees:
High school: 3-year Science program 1995

Bachelor of Arts in Psychology, 2001at University of California, Los Angeles,
USA

Master Thesis in Psychology, 2003
“Spatial learning and memory deficits in the adult rat following neonatal corticosterone and ketamine administration”
Inst for Social Sciences, Div for Psychology, University of Karlstad, Inst of Physiology and Pharmacology, Div for Pharmacology, Univ of Göteborg, Sweden

Research student, Institute of Physiology and Neuroscience, Div for Pharmacoloy
Sahlgrenska Academy, Göteborgs University 2002-03

PhD student, Institute of Physiology, and Neuroscience, Div for Pharmacoloy
Sahlgrenska Academy, Göteborgs University, 2003-07

PhD in medicine 2007, Doctoral thesis “Cognition and social behaviour
in schizophrenia. An animal model investigating the potential role of nitric oxide. “

Publications:
Klamer D, Palsson E, Wass C, Engel JA, Archer T, Svensson L,
(2005). Antagonism of the nitric oxide synthase inhibitor, L-NAME, of the
effects on phencyclidine on latent inhibition in taste aversion conditioning.
Behav Brain Research, 161, 60-68.

Palsson E., Fejgin K., Wass C, Engel J. A., Svensson L. & Klamer
D. (2007) The amino acid L: -lysine blocks the disruptive effect of
phencyclidine on prepulse inhibition in mice. Psychopharmacology (Berl).

Svensson J, Diez M, Engel J, Wass C, Tivesten A, Jansson J O,
Isaksson O, Archer T, Hokfeldt T. & Ohlsson C. (2006) Endocrine, liverderived
IGF-I is of importance for spatial learning and memory in old
mice. J Endocrinol, 189, 617-27.

Wass C, Klamer D, Palsson E, Fejgin K, Engel JA, Archer T,
Svensson L, (2006). The nitric oxide synthase inhibitor, L-NAME, reverses
phencyclidine-induced disruption of spatial reference learning. Behavioural
Brain Research,15;171(1):147-53.

Wass, C, Archer, T, Palsson, E, Fejgin, K, Alexandersson, A,
Klamer, D, Engel, J. A. & Svensson, L. (2006) Phencyclidine affects
memory in a nitric oxide-dependent manner: Working and reference
memory. Behav Brain Res, 174, 49-55.

Svensson L, Zhang J, Johansson C, Fejgin K, Palsson E, Wass C,
Klamer D, Jackson DM, Engel JA, (2006). Behavioural effects of
phencyclidine: dependence on Ca2 and nitric oxide signalling. In: Di
Chiara G, Carboni E, Valentini V, Acquas E, Bassareo V, Cadoni C (eds)
Monitoring Molecules in Neuroscience, Cagliari, pp 563-565.

Fejgin, K., Palsson, E., Wass, C., Svensson, L. & Klamer, D. (2007a)
Nitric Oxide Signaling in the Medial Prefrontal Cortex is Involved in the
Biochemical and Behavioral Effects of Phencyclidine. Neuropsychopharmacology.

Fegin, K., Safonov, S., Palsson, E., Wass, C., Eengel, J. A., Svensson, L.
& Klamer, D. (2007b) The atypical antipsychotic, aripiprazole, blocks
phencyclidine-induced disruption of prepulse inhibition in mice. Psychopharmacology
(Berl).

Wass, C., Svensson, L., Fejgin, K., Palsson, E., Archer, T., Engel, J.
A. & Klamer, D. (2008) Nitric oxide synthase inhibition attenuates
phencyclidine-induced disruption of cognitive flexibility. Pharmacol Biochem
Behav, 89, 352-9.

Palsson, E., Fejgin, K. Wass, C, & Klamer, D. (2008) Agmatine attenuates the disruptive
effects of phencycidine on prepulse inhibition. European Journal of Pharmacology, 590, 212-
16.

Fejgin K, Palsson E, Wass C, Svensson L, Klamer D (2008) Nitric oxide signaling in the
medial prefrontal cortex is involved in the biochemical and behavioral effects of
phencyclidine. Neuropsychopharmacology 33: 1874-83
Wass C, Klamer D, Fejgin K, Palsson E (2009) The importance of nitric oxide in social
dysfunction. Behav Brain Res, 2009 Jan 8. [Epub ahead of print]

Fejgin K, Palsson E, Wass C, Finnerty N, Lowry J, Klamer D (2009) Prefrontal GABA(
B) Receptor Activation Attenuates Phencyclidine-Induced Impairments of Prepulse
Inhibition: Involvement of Nitric Oxide. Neuropsychopharmacology, 2009 Jan 14. [Epub
ahead of print]

Wallen-Mackenzie A, Nordenankar K, Fejgin K, Lagerstrom MC, Emilsson L, Freriksson
R, Wass C, Andersson D, Egecioglu E, Andersson M, Strandberg J, Lindhe O,
Schioth HB, Chergui K, Hanse E, Langstrom B, Fredriksson A, Svensson L, Roman E,
Kullander K (2009) Restricted cortical and amygdaloid removal of vesicular glutamate
transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry
of higher brain function. J Neurosci 29: 2238-51